Urticaria & Angioedema
Urticaria (hives) and angioedema are common signs of a vascular reaction in the skin. Urticaria appears as itchy, superficial raised welts on the skin surface, whereas angioedema is deeper swelling in the dermis and subcutaneous tissue that usually affects thin-skinned areas such as the eyes, lips or genitals.
At Haute-Derma, we see these conditions not just as a skin problem but as an immune system puzzle. Our approach focuses on finding the underlying cause, whether allergy, infection or autoimmunity, so we can stop the itch for good and prevent dangerous complications such as airway swelling.
Our Approach to Treating Urticaria and Angioedema
Our specialists at Haute-Derma use a multi-tiered treatment strategy. In acute cases, the goal is to shut down the allergic reaction quickly. For chronic urticaria (lasting more than 6 weeks), we carry out detailed tests to understand why the mast cells are overactive.
We know how distressing the itching and visible swelling can be. At Haute-Derma, we favor modern non-drowsy antihistamines combined with up-to-date immunomodulating therapies to help you feel comfortable in daily life again.
Our comprehensive management program includes:
- Screening for allergens (food, medication, environment) and physical triggers.
- High-dose antihistamine therapy in line with international guidelines (EAACI/GA²LEN).
- Biologic treatment (omalizumab) for chronic urticaria that does not respond to standard medication.
How We Diagnose Urticaria and Angioedema at Haute-Derma
Haute-Derma follows a thorough diagnostic process to classify the condition and find its cause:
- Urticaria: Pink or red welts surrounded by a red flare, ranging from a few millimeters to several centimeters across.
- Angioedema: Tense swelling that is more painful than itchy, typically on the lips, eyelids or tongue.
- Duration: We determine whether the urticaria is acute (less than 6 weeks) or chronic (more than 6 weeks).
- Physical provocation tests: Tests with pressure, heat, cold or friction identify physical urticaria.
- Laboratory tests: A complete blood count, inflammatory markers (CRP), thyroid function and, if needed, screening for autoantibodies.
- Ruling out hereditary angioedema (HAE): C4 and C1 esterase inhibitor levels are checked if you have recurrent angioedema without hives.
How Are Urticaria and Angioedema Treated at Haute-Derma?
Our treatment aims to block the release of histamine and other inflammatory mediators:
- Second-generation H1 antihistamines: The first-line choice. For hard-to-control cases, we may increase the dose up to fourfold, in line with international guidelines.
- Leukotriene receptor antagonists: Added to antihistamines to boost their effect, particularly in urticaria triggered by food or medication.
- Biologic therapy (omalizumab): A major advance we offer at Haute-Derma for chronic spontaneous urticaria. It works by binding IgE antibodies, clearing the skin quickly and for the long term.
- Short courses of corticosteroids: Used only for severe acute flares or angioedema threatening the airway, to bring inflammation under control quickly.
- Elimination diet advice: We help you recognize and avoid histamine-releasing foods (such as fermented foods, seafood and wine).
